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Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex

Paf1 complex (Paf1C) is a transcription elongation factor whose recruitment is stimulated by Spt5 and the CDKs Kin28 and Bur1, which phosphorylate the Pol II C-terminal domain (CTD) on Serines 2, 5, and 7. Bur1 promotes Paf1C recruitment by phosphorylating C-terminal repeats (CTRs) in Spt5, and we s...

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Bibliografiset tiedot
Päätekijät: Qiu, Hongfang, Hu, Cuihua, Gaur, Naseem A, Hinnebusch, Alan G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419927/
https://ncbi.nlm.nih.gov/pubmed/22796944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.188
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