Phosphorylated Pol II CTD recruits multiple HDACs, including Rpd3C(S), for methylation-dependent deacetylation of ORF nucleosomes

Methylation of histone H3 by Set1 and Set2 is required for deacetylation of nucleosomes in coding regions by histone deacetylase complexes (HDACs) Set3C and Rpd3C(S), respectively. We report that Set3C and Rpd3C(S) are co-transcriptionally recruited in the absence of Set1 and Set2, but in a manner s...

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Autores principales: Govind, Chhabi K., Qiu, Hongfang, Ginsburg, Daniel S., Ruan, Chun, Hofmeyer, Kimberly, Hu, Cuihua, Swaminathan, Venkatesh, Workman, Jerry L., Li, Bing, Hinnebusch, Alan G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937259/
https://ncbi.nlm.nih.gov/pubmed/20670892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.07.003
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