Phosphorylated Pol II CTD recruits multiple HDACs, including Rpd3C(S), for methylation-dependent deacetylation of ORF nucleosomes

Methylation of histone H3 by Set1 and Set2 is required for deacetylation of nucleosomes in coding regions by histone deacetylase complexes (HDACs) Set3C and Rpd3C(S), respectively. We report that Set3C and Rpd3C(S) are co-transcriptionally recruited in the absence of Set1 and Set2, but in a manner s...

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Detalhes bibliográficos
Main Authors: Govind, Chhabi K., Qiu, Hongfang, Ginsburg, Daniel S., Ruan, Chun, Hofmeyer, Kimberly, Hu, Cuihua, Swaminathan, Venkatesh, Workman, Jerry L., Li, Bing, Hinnebusch, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937259/
https://ncbi.nlm.nih.gov/pubmed/20670892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.07.003
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