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Phosphorylation of the Pol II CTD by KIN28 enhances BUR1/BUR2 recruitment and Ser2 CTD phosphorylation near promoters

Cyclin-dependent kinase BUR1/BUR2 appears to be the yeast ortholog of P-TEFb, which phosphorylates Ser2 of the RNA Pol II CTD, but the importance of BUR1/BUR2 in CTD phosphorylation is unclear. We show that BUR1/BUR2 is co-transcriptionally recruited to the 5′ end of ARG1 in a manner stimulated by i...

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Detalhes bibliográficos
Main Authors: Qiu, Hongfang, Hu, Cuihua, Hinnebusch, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683426/
https://ncbi.nlm.nih.gov/pubmed/19328068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.02.018
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