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Alternating access mechanism in the POT family of oligopeptide transporters

Short chain peptides are actively transported across membranes as an efficient route for dietary protein absorption and for maintaining cellular homeostasis. In mammals, peptide transport occurs via PepT1 and PepT2, which belong to the proton-dependent oligopeptide transporter, or POT family. The re...

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Autori principali: Solcan, Nicolae, Kwok, Jane, Fowler, Philip W, Cameron, Alexander D, Drew, David, Iwata, So, Newstead, Simon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419923/
https://ncbi.nlm.nih.gov/pubmed/22659829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.157
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