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Transcriptional networks driving enhancer function in the CFTR gene

A critical cis-regulatory element for the cystic fibrosis transmembrane conductance regulator (CFTR) gene is located in intron 11, 100 kb distal to the promoter, with which it interacts. This sequence contains an intestine-selective enhancer and associates with enhancer signature proteins, such as p...

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Detalhes bibliográficos
Main Authors: Kerschner, Jenny L, Harris, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419791/
https://ncbi.nlm.nih.gov/pubmed/22671145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120693
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