Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation

BACKGROUND: The mechanisms of progressive dopaminergic neuronal loss in Parkinson’s disease (PD) remain poorly understood, largely due to the complex etiology and multifactorial nature of disease pathogenesis. Several lines of evidence from human studies and experimental models over the last decade...

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Detalhes bibliográficos
Main Authors: Gordon, Richard, Anantharam, Vellareddy, Kanthasamy, Anumantha G, Kanthasamy, Arthi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419619/
https://ncbi.nlm.nih.gov/pubmed/22540228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-82
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