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From loss to gain: role for SUN1 in laminopathies

Mutations in LMNA encoding lamins A and C are associated with at least 10 different degenerative disorders affecting diverse tissues, collectively called laminopathies. A recent study showed that mis-accumulation of SUN1 underlies the pathology of degenerative features in laminopathies, and concomit...

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Detalhes bibliográficos
Main Authors: Liu, Baohua, Jin, Dong-Yan, Zhou, Zhongjun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419603/
https://ncbi.nlm.nih.gov/pubmed/22709970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-2-21
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