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Reversal of laminopathies: the curious case of SUN1
Mutations in the LMNA gene are associated with a spectrum of human dystrophic diseases termed the “nuclear laminopathies.” We recently found that the accumulation of the inner nuclear envelope proteins SUN1 is pathogenic in progeric and dystrophic laminopathies. This conclusion arose from the unexpe...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474661/ https://ncbi.nlm.nih.gov/pubmed/22895095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.21714 |
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