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Reversal of laminopathies: the curious case of SUN1

Mutations in the LMNA gene are associated with a spectrum of human dystrophic diseases termed the “nuclear laminopathies.” We recently found that the accumulation of the inner nuclear envelope proteins SUN1 is pathogenic in progeric and dystrophic laminopathies. This conclusion arose from the unexpe...

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Detalhes bibliográficos
Main Authors: Chi, Ya-hui, Chen, Chia-yen, Jeang, Kuan-Teh
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474661/
https://ncbi.nlm.nih.gov/pubmed/22895095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.21714
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