Mammalian SUN Protein Interaction Networks at the Inner Nuclear Membrane and Their Role in Laminopathy Disease Processes

The nuclear envelope (NE) LINC complex, in mammals comprised of SUN domain and nesprin proteins, provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity. SUN1 and SUN2 interact with lamin A, but lamin A is only requ...

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Detalhes bibliográficos
Main Authors: Haque, Farhana, Mazzeo, Daniela, Patel, Jennifer T., Smallwood, Dawn T., Ellis, Juliet A., Shanahan, Catherine M., Shackleton, Sue
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823409/
https://ncbi.nlm.nih.gov/pubmed/19933576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.071910
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