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Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion

Metastasis to bone, liver and lungs is the primary cause of death in breast cancer patients. Our studies have revealed that the novel tumor suppressor Pdcd4 inhibits breast cancer cell migration and invasion in vitro. Loss of Pdcd4 in human nonmetastatic breast cancer cells increased the expression...

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Autori principali: Santhanam, AN, Baker, AR, Hegamyer, G, Kirschmann, DA, Colburn, NH
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419530/
https://ncbi.nlm.nih.gov/pubmed/20498644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.158
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