Pathological Consequences of Long-Term Mitochondrial Oxidative Stress in the Mouse Retinal Pigment Epithelium

Oxidative stress in the retinal pigment epithelium (RPE) is hypothesized to be a major contributor to the development of age-related macular degeneration (AMD). Mitochondrial manganese superoxide dismutase (MnSOD) is a critical antioxidant protein that scavenges the highly reactive superoxide radica...

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Hoofdauteurs: Seo, Soo-jung, Krebs, Mark P., Mao, Haoyu, Jones, Kyle, Conners, Mandy, Lewin, Alfred S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419481/
https://ncbi.nlm.nih.gov/pubmed/22687918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2012.05.013
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