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Effect of valproic acid on mitochondrial epigenetics
Valproic acid (valproate), an anticonvulsant and a mood stabilizer, is a potent histone deacetylase inhibitor and a widely utilized pharmacological tool for neuroepigenetic research including DNA methylation. However, only nuclear but not mitochondrial DNA (mtDNA) has been investigated for the effec...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2012
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3419440/ https://ncbi.nlm.nih.gov/pubmed/22728245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.06.019 |
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