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Effect of valproic acid on mitochondrial epigenetics

Valproic acid (valproate), an anticonvulsant and a mood stabilizer, is a potent histone deacetylase inhibitor and a widely utilized pharmacological tool for neuroepigenetic research including DNA methylation. However, only nuclear but not mitochondrial DNA (mtDNA) has been investigated for the effec...

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Hlavní autoři: Chen, Hu, Dzitoyeva, Svetlana, Manev, Hari
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419440/
https://ncbi.nlm.nih.gov/pubmed/22728245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.06.019
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