RNA Inhibition Highlights Cyclin D1 as a Potential Therapeutic Target for Mantle Cell Lymphoma

Mantle cell lymphoma is characterized by a genetic translocation results in aberrant overexpression of the CCND1 gene, which encodes cyclin D1. This protein functions as a regulator of the cell cycle progression, hence is considered to play an important role in the pathogenesis of the disease. In th...

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Autors principals: Weinstein, Shiri, Emmanuel, Rafi, Jacobi, Ashley M., Abraham, Avigdor, Behlke, Mark A., Sprague, Andrew G., Novobrantseva, Tatiana I., Nagler, Arnon, Peer, Dan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419170/
https://ncbi.nlm.nih.gov/pubmed/22905260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043343
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