Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies

Despite progress in systemic small interfering RNA (siRNA) delivery to the liver and to solid tumors, systemic siRNA delivery to leukocytes remains challenging. The ability to silence gene expression in leukocytes has great potential for identifying drug targets and for RNAi-based therapy for leukoc...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Weinstein, Shiri, Toker, Itai A., Emmanuel, Rafi, Ramishetti, Srinivas, Hazan-Halevy, Inbal, Rosenblum, Daniel, Goldsmith, Meir, Abraham, Avigdor, Benjamini, Ohad, Bairey, Osnat, Raanani, Pia, Nagler, Arnon, Lieberman, Judy, Peer, Dan
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2016
主題:
PNAS Plus
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711827/
https://ncbi.nlm.nih.gov/pubmed/26699502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519273113
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