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BCR-Induced Superoxide Negatively Regulates B Cell Proliferation and T cell-independent type 2 Antibody Responses

Superoxide and its derivatives have been implicated as secondary messenger molecules that influence signaling cascades in non-phagocytes. B lymphocytes produce superoxide after BCR ligation. We found that these reactive oxygen species (ROS) regulate B cell signaling and entry into the cell cycle. B...

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Bibliografski detalji
Glavni autori: Richards, Sabrina M., Clark, Edward A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419136/
https://ncbi.nlm.nih.gov/pubmed/19877015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939587
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