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BCR-Induced Superoxide Negatively Regulates B Cell Proliferation and T cell-independent type 2 Antibody Responses
Superoxide and its derivatives have been implicated as secondary messenger molecules that influence signaling cascades in non-phagocytes. B lymphocytes produce superoxide after BCR ligation. We found that these reactive oxygen species (ROS) regulate B cell signaling and entry into the cell cycle. B...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3419136/ https://ncbi.nlm.nih.gov/pubmed/19877015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939587 |
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