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CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes

BACKGROUND: HIV latency is an obstacle for the eradication of HIV from infected individuals. Stable post-integration latency is controlled principally at the level of transcription. The HIV trans-activating protein, Tat, plays a key function in enhancing HIV transcriptional elongation. The HIV core...

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Bibliografiske detaljer
Main Authors: Wilhelm, Emmanuelle, Doyle, Marie-Christine, Nzaramba, Isaac, Magdzinski, Alexandre, Dumais, Nancy, Bell, Brendan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419132/
https://ncbi.nlm.nih.gov/pubmed/22834489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-62
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