An NH2-Terminal Multi-Basic RKR Motif Is Required for the ATP-Dependent Regulation of hIK1

We previously demonstrated that the ATP/PKA‑dependent activation of the human intermediate conductance, Ca(2+)‑activated K(+) channel, hIK1, is dependent upon a C‑terminal motif. The NH(2)‑terminus of hIK1 contains a multi‑basic (13)RRRKR(17) motif, known to be important in the trafficking and funct...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jones, Heather M., Bailey, Mark A., Baty, Catherine J., MacGregor, Gordon G., Syme, Colin A., Hamilton, Kirk L., Devor, Daniel C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2007
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419011/
https://ncbi.nlm.nih.gov/pubmed/18690018
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