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The Role of NH(2)-terminal Positive Charges in the Activity of Inward Rectifier K(ATP) Channels
Approximately half of the NH(2) terminus of inward rectifier (Kir) channels can be deleted without significant change in channel function, but activity is lost when more than ∼30 conserved residues before the first membrane spanning domain (M1) are removed. Systematic replacement of the positive cha...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229524/ https://ncbi.nlm.nih.gov/pubmed/12198096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028621 |
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