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Multiple Inhibitory G-Protein-Coupled Receptors Resist Acute Desensitization in the Presynaptic But Not Postsynaptic Compartments of Neurons

Acute desensitization is a common property of G(i/o)-coupled receptors. Recent data, however, suggest that, unlike μ-opioid receptors (MORs) located somatodendritically in neurons or expressed in heterologous systems, MORs in the presynaptic compartment of neurons are resistant to acute desensitizat...

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Autors principals: Pennock, Reagan L., Dicken, Matthew S., Hentges, Shane T.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418873/
https://ncbi.nlm.nih.gov/pubmed/22836254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1227-12.2012
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