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Desensitization-resistant and -sensitive GPCR-mediated inhibition of GABA release occurs by Ca(2+)-dependent and -independent mechanisms at a hypothalamic synapse

Whereas the activation of Gα(i/o)-coupled receptors commonly results in postsynaptic responses that show acute desensitization, the presynaptic inhibition of transmitter release caused by many Gα(i/o)-coupled receptors is maintained during agonist exposure. However, an exception has been noted where...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Neurophysiol
Κύριοι συγγραφείς: Pennock, Reagan L., Hentges, Shane T.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Physiological Society 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922459/
https://ncbi.nlm.nih.gov/pubmed/26912590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00535.2015
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