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Desensitization-resistant and -sensitive GPCR-mediated inhibition of GABA release occurs by Ca(2+)-dependent and -independent mechanisms at a hypothalamic synapse
Whereas the activation of Gα(i/o)-coupled receptors commonly results in postsynaptic responses that show acute desensitization, the presynaptic inhibition of transmitter release caused by many Gα(i/o)-coupled receptors is maintained during agonist exposure. However, an exception has been noted where...
Tallennettuna:
| Julkaisussa: | J Neurophysiol |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Physiological Society
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922459/ https://ncbi.nlm.nih.gov/pubmed/26912590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00535.2015 |
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