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Targeting the Reversibly Oxidized Protein Tyrosine Phosphatase Superfamily

Controlled production of reactive oxygen species leads to reversible oxidation of protein tyrosine phosphatases (PTPs) and has emerged as an important tier of regulation over phosphorylation-dependent signal transduction. We present a modified cysteinyl-labeling assay that detects reversible oxidati...

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Detalhes bibliográficos
Main Authors: Boivin, Benoit, Yang, Ming, Tonks, Nicholas K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418810/
https://ncbi.nlm.nih.gov/pubmed/20807953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.3137pl2
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