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A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells

The production of reactive oxygen species (ROS) exerts an additional tier of control over tyrosine phosphorylation-dependent signal transduction by transiently inhibiting the catalytic activity of specific protein tyrosine phosphatases (PTPs). Hence, the ability to detect reversible oxidation of PTP...

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Detalhes bibliográficos
Main Authors: Boivin, Benoit, Zhang, Sheng, Arbiser, Jack L., Zhang, Zhong-Yin, Tonks, Nicholas K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481340/
https://ncbi.nlm.nih.gov/pubmed/18632564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804336105
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