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Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin

Neocortical neurons have highly branched dendritic trees that are essential for their function. Indeed, defects in dendritic arborization are associated with human neurodevelopmental disorders. The molecular mechanisms regulating dendritic arbor complexity, however, are still poorly understood. Here...

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Main Authors: Rosário, Marta, Schuster, Steffen, Jüttner, René, Parthasarathy, Srinivas, Tarabykin, Victor, Birchmeier, Walter
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418591/
https://ncbi.nlm.nih.gov/pubmed/22810622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.191593.112
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