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Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin

Neocortical neurons have highly branched dendritic trees that are essential for their function. Indeed, defects in dendritic arborization are associated with human neurodevelopmental disorders. The molecular mechanisms regulating dendritic arbor complexity, however, are still poorly understood. Here...

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Hlavní autoři: Rosário, Marta, Schuster, Steffen, Jüttner, René, Parthasarathy, Srinivas, Tarabykin, Victor, Birchmeier, Walter
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418591/
https://ncbi.nlm.nih.gov/pubmed/22810622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.191593.112
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