Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin

Neocortical neurons have highly branched dendritic trees that are essential for their function. Indeed, defects in dendritic arborization are associated with human neurodevelopmental disorders. The molecular mechanisms regulating dendritic arbor complexity, however, are still poorly understood. Here...

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Autores principales: Rosário, Marta, Schuster, Steffen, Jüttner, René, Parthasarathy, Srinivas, Tarabykin, Victor, Birchmeier, Walter
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418591/
https://ncbi.nlm.nih.gov/pubmed/22810622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.191593.112
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