Overexpression of cell cycle regulator CDCA3 promotes oral cancer progression by enhancing cell proliferation with prevention of G1 phase arrest

BACKGROUND: Cell division cycle associated 3 (CDCA3), part of the Skp1-cullin-F-box (SCF) ubiquitin ligase, refers to a trigger of mitotic entry and mediates destruction of the mitosis inhibitory kinase. Little is known about the relevance of CDCA3 to human malignancy including oral squamous cell ca...

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Autors principals: Uchida, Fumihiko, Uzawa, Katsuhiro, Kasamatsu, Atsushi, Takatori, Hiroaki, Sakamoto, Yosuke, Ogawara, Katsunori, Shiiba, Masashi, Tanzawa, Hideki, Bukawa, Hiroki
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418557/
https://ncbi.nlm.nih.gov/pubmed/22839099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-321
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