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A novel zebrafish model of hyperthermia-induced seizures reveals a role for TRPV4 channels and NMDA-type glutamate receptors

Febrile seizures are the most common seizure type in children under the age of five, but mechanisms underlying seizure generation in vivo remain unclear. Animal models to address this issue primarily focus on immature rodents heated indirectly using a controlled water bath or air blower. Here we des...

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Autors principals: Hunt, Robert F., Hortopan, Gabriela A., Gillespie, Anna, Baraban, Scott C.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418450/
https://ncbi.nlm.nih.gov/pubmed/22735490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.06.013
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