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Spontaneous Seizures and Altered Gene Expression in GABA Signaling Pathways in a mind bomb Mutant Zebrafish

Disruption of E3 ubiquitin ligase activity in immature zebrafish mind bomb mutants leads to a failure in Notch signaling, excessive numbers of neurons, and depletion of neural progenitor cells. This neurogenic phenotype is associated with defects in neural patterning and brain development. Because d...

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Detalhes bibliográficos
Main Authors: Hortopan, Gabriela A., Dinday, Matthew T., Baraban, Scott C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962868/
https://ncbi.nlm.nih.gov/pubmed/20943912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1887-10.2010
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