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Aberrant expression of genes necessary for neuronal development and Notch signaling in an epileptic mind bomb zebrafish
Mutation within an ubiquitin E3 ligase gene can lead to a failure in Notch signaling, excessive neurons, and depletion of neural progenitor cells in mind bomb mutants. Using mib(hi904) zebrafish, we reported seizures and a down-regulation of GABA signaling pathway genes. A transcriptome analysis als...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137702/ https://ncbi.nlm.nih.gov/pubmed/21688347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22680 |
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