The Akt-SRPK-SR Axis Constitutes a Major Pathway in Transducing EGF Signaling to Regulate Alternative Splicing in the Nucleus

Pre-mRNA splicing is regulated by developmental and environmental cues, but little is known about how specific signals are transduced in mammalian cells to regulate this critical gene expression step. Here, we report massive reprogramming of alternative splicing in response to EGF signaling. By bloc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhou, Zhihong, Qiu, Jinsong, Wen, Liu, Zhou, Yu, Plocinik, Ryan M., Li, Hairi, Hu, Qidong, Ghosh, Gourisanker, Adams, Joseph A., Rosenfeld, Michael G., Fu, Xiang-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418396/
https://ncbi.nlm.nih.gov/pubmed/22727668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados