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Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor
LIF (leukaemia inhibitory factor) is a key cytokine for maintaining self-renewal and pluripotency of mESCs (mouse embryonic stem cells). Upon binding to the LIF receptor, LIF activates three major intracellular signalling pathways: the JAK (Janus kinase)/STAT3 (signal transducer and activator of tra...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418323/ https://ncbi.nlm.nih.gov/pubmed/21793804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20102152 |
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