STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells

Nu61, a radiation-resistant human tumor xenograft, was selected from a parental radiosensitive tumor SCC-61 by eight serial cycles of passage in athymic nude mice and in vivo irradiation. Replicate DNA array experiments identified 52 genes differentially expressed in nu61 tumors compared with SCC-61...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Khodarev, Nikolai N., Beckett, Michael, Labay, Edwardine, Darga, Thomas, Roizman, Bernard, Weichselbaum, Ralph R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341831/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14755057/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308102100
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