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Overexpression of Guanylate Cyclase Activating Protein 2 in Rod Photoreceptors In Vivo Leads to Morphological Changes at the Synaptic Ribbon

Guanylate cyclase activating proteins are EF-hand containing proteins that confer calcium sensitivity to retinal guanylate cyclase at the outer segment discs of photoreceptor cells. By making the rate of cGMP synthesis dependent on the free intracellular calcium levels set by illumination, GCAPs pla...

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Bibliografiska uppgifter
Huvudupphovsmän: López-del Hoyo, Natalia, Fazioli, Lucrezia, López-Begines, Santiago, Fernández-Sánchez, Laura, Cuenca, Nicolás, Llorens, Jordi, de la Villa, Pedro, Méndez, Ana
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418235/
https://ncbi.nlm.nih.gov/pubmed/22912773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042994
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