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Insights on the trafficking and retro-translocation of glycosphingolipid-binding bacterial toxins

Some bacterial toxins and viruses have evolved the capacity to bind mammalian glycosphingolipids to gain access to the cell interior, where they can co-opt the endogenous mechanisms of cellular trafficking and protein translocation machinery to cause toxicity. Cholera toxin (CT) is one of the best-s...

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Autors principals: Cho, Jin A., Chinnapen, Daniel J.-F., Aamar, Emil, te Welscher, Yvonne M., Lencer, Wayne I., Massol, Ramiro
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417474/
https://ncbi.nlm.nih.gov/pubmed/22919642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2012.00051
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