Fasitibant chloride, a kinin B(2) receptor antagonist, and dexamethasone interact to inhibit carrageenan-induced inflammatory arthritis in rats

BACKGROUND AND PURPOSE: Bradykinin, through the kinin B(2) receptor, is involved in inflammatory processes related to arthropathies. B(2) receptor antagonists inhibited carrageenan-induced arthritis in rats in synergy with anti-inflammatory steroids. The mechanism(s) underlying this drug interaction...

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Библиографические подробности
Главные авторы: Valenti, Claudio, Giuliani, Sandro, Cialdai, Cecilia, Tramontana, Manuela, Maggi, Carlo Alberto
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2012
Предметы:
Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417455/
https://ncbi.nlm.nih.gov/pubmed/22251015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01861.x
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