Fasitibant chloride, a kinin B(2) receptor antagonist, and dexamethasone interact to inhibit carrageenan-induced inflammatory arthritis in rats

BACKGROUND AND PURPOSE: Bradykinin, through the kinin B(2) receptor, is involved in inflammatory processes related to arthropathies. B(2) receptor antagonists inhibited carrageenan-induced arthritis in rats in synergy with anti-inflammatory steroids. The mechanism(s) underlying this drug interaction...

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Main Authors: Valenti, Claudio, Giuliani, Sandro, Cialdai, Cecilia, Tramontana, Manuela, Maggi, Carlo Alberto
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2012
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Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417455/
https://ncbi.nlm.nih.gov/pubmed/22251015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01861.x
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