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Urantide: an ultrapotent urotensin II antagonist peptide in the rat aorta
In this study we describe the ability of two human urotensin-II (hU-II) derivatives [Pen(5),Orn(8)]hU-II(4–11) and [Pen(5),DTrp(7),Orn(8)]hU-II(4–11) (urantide) to block hU-II-induced contractions in the rat isolated thoracic aorta. Both compounds competitively antagonized hU-II- induced effects wit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574141/ https://ncbi.nlm.nih.gov/pubmed/14645137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705555 |
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