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Gamma-secretase inhibitor enhances the cytotoxic effect of bortezomib in multiple myeloma
BACKGROUND: Targeting of Notch signaling with γ-secretase inhibitors (GSIs) has been considered a promising strategy for the treatment of hematological malignancies including multiple myeloma (MM). Here we investigated whether the cytotoxic effect of bortezomib, an agent commonly used in MM, could b...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3417352/ https://ncbi.nlm.nih.gov/pubmed/21965140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-011-0060-6 |
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