A heparan sulfate-targeted conditionally replicative adenovirus, Ad5.pk7-Δ24, for the treatment of advanced breast cancer

Conditionally replicating adenoviruses (CRAds) that replicate in tumor but less in normal cells are promising anticancer agents. A major determinant of their potency is their capacity for infecting target cells. The primary receptor for serotype 5 adenovirus (Ad5), the most widely used serotype in g...

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Detalhes bibliográficos
Main Authors: Ranki, T, Kanerva, A, Ristimäki, A, Hakkarainen, T, Särkioja, M, Kangasniemi, L, Raki, M, Laakkonen, P, Goodison, S, Hemminki, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417341/
https://ncbi.nlm.nih.gov/pubmed/16900223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3302830
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