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A conditionally replicative adenovirus that codes for a TK-GFP fusion protein (Ad5 Δ24TK-GFP) for evaluation of the potency of oncolytic virotherapy combined with molecular chemotherapy
The utility of conditionally replicative adenoviruses (CRAds) in cancer gene therapy is based on their ability to destroy tumor cells by oncolysis. However, in order to achieve adequate therapeutic response, CRAds have to spread through the tumor tissue by replication. Thus, to study the potency of...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2203218/ https://ncbi.nlm.nih.gov/pubmed/16964432 |
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