Molecular Target Modulation, Imaging, and Clinical Evaluation of Gastrointestinal Stromal Tumor Patients Treated with Sunitinib Malate after Imatinib Failure

PURPOSE: To evaluate sunitinib activity and potential cellular and molecular correlates in gastrointestinal stromal tumor (GIST) patients after imatinib failure, in addition to assessing the safety and pharmacokinetics (PK) of different dose schedules. EXPERIMENTAL DESIGN: In this open-label, dose-r...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Demetri, George D., Heinrich, Michael C., Fletcher, Jonathan A., Fletcher, Christopher D.M., Van den Abbeele, Annick D., Corless, Christopher L., Antonescu, Cristina R., George, Suzanne, Morgan, Jeffrey A., Chen, Ming Hui, Bello, Carlo L., Huang, Xin, Cohen, Darrel P., Baum, Charles M., Maki, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417101/
https://ncbi.nlm.nih.gov/pubmed/19737946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0482
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares