Molecular Target Modulation, Imaging, and Clinical Evaluation of Gastrointestinal Stromal Tumor Patients Treated with Sunitinib Malate after Imatinib Failure

PURPOSE: To evaluate sunitinib activity and potential cellular and molecular correlates in gastrointestinal stromal tumor (GIST) patients after imatinib failure, in addition to assessing the safety and pharmacokinetics (PK) of different dose schedules. EXPERIMENTAL DESIGN: In this open-label, dose-r...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Demetri, George D., Heinrich, Michael C., Fletcher, Jonathan A., Fletcher, Christopher D.M., Van den Abbeele, Annick D., Corless, Christopher L., Antonescu, Cristina R., George, Suzanne, Morgan, Jeffrey A., Chen, Ming Hui, Bello, Carlo L., Huang, Xin, Cohen, Darrel P., Baum, Charles M., Maki, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417101/
https://ncbi.nlm.nih.gov/pubmed/19737946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0482
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados