CD57(high) Neuroblastoma Cells Have Aggressive Attributes Ex Situ and an Undifferentiated Phenotype in Patients

BACKGROUND: Neuroblastoma is thought to originate from neural crest-derived cells. CD57 defines migratory neural crest cells in normal development and is expressed in neuroblastoma. METHODOLOGY AND PRINCIPAL FINDINGS: We investigated the role of CD57 expression in neuroblastoma cells ex situ and in...

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Main Authors: Schlitter, Anne-Marie, Dorneburg, Carmen, Barth, Thomas F. E., Wahl, Joachim, Schulte, Johannes H., Brüderlein, Silke, Debatin, Klaus-Michael, Beltinger, Christian
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416815/
https://ncbi.nlm.nih.gov/pubmed/22900004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042025
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