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Pertussis Toxin, an Inhibitor of G(αi) PCR, Inhibits Bile Acid- and Cytokine-Induced Apoptosis in Primary Rat Hepatocytes

Excessive hepatocyte apoptosis is a common event in acute and chronic liver diseases leading to loss of functional liver tissue. Approaches to prevent apoptosis have therefore high potential for the treatment of liver disease. G-protein coupled receptors (GPCR) play crucial roles in cell fate (proli...

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Autores principales: Karimian, Golnar, Buist-Homan, Manon, Faber, Klaas Nico, Moshage, Han
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416748/
https://ncbi.nlm.nih.gov/pubmed/22900098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043156
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