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Microbicidal Activity of Vascular Peroxidase 1 in Human Plasma via Generation of Hypochlorous Acid

Members of the heme peroxidase family play an important role in host defense. Myeloperoxidase (MPO) is expressed in phagocytes and is the only animal heme peroxidase previously reported to be capable of using chloride ion as a substrate to form the highly microbicidal species hypochlorous acid (HOCl...

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Detalhes bibliográficos
Main Authors: Li, Hong, Cao, Zehong, Moore, D. Ray, Jackson, Patricia L., Barnes, Stephen, Lambeth, J. David, Thannickal, Victor J., Cheng, Guangjie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416459/
https://ncbi.nlm.nih.gov/pubmed/22526679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.06337-11
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