Microbicidal Activity of Vascular Peroxidase 1 in Human Plasma via Generation of Hypochlorous Acid

Members of the heme peroxidase family play an important role in host defense. Myeloperoxidase (MPO) is expressed in phagocytes and is the only animal heme peroxidase previously reported to be capable of using chloride ion as a substrate to form the highly microbicidal species hypochlorous acid (HOCl...

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Main Authors: Li, Hong, Cao, Zehong, Moore, D. Ray, Jackson, Patricia L., Barnes, Stephen, Lambeth, J. David, Thannickal, Victor J., Cheng, Guangjie
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416459/
https://ncbi.nlm.nih.gov/pubmed/22526679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.06337-11
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