Proteome-Wide Overexpression of Host Proteins for Identification of Factors Affecting Tombusvirus RNA Replication: an Inhibitory Role of Protein Kinase C

To identify host genes affecting replication of Tomato bushy stunt virus (TBSV), a small model positive-stranded RNA virus, we overexpressed 5,500 yeast proteins individually in Saccharomyces cerevisiae, which supports TBSV replication. In total, we identified 141 host proteins, and overexpression o...

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Detalhes bibliográficos
Main Authors: Shah Nawaz-ul-Rehman, Muhammad, Martinez-Ochoa, Natalia, Pascal, Helene, Sasvari, Zsuzsanna, Herbst, Christin, Xu, Kai, Baker, Jannine, Sharma, Monika, Herbst, Alan, Nagy, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416130/
https://ncbi.nlm.nih.gov/pubmed/22718827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00019-12
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