Pathogenic Consequences of Vaginal Infection with CCR5-Tropic Simian-Human Immunodeficiency Virus SHIV(SF162P3N)

We previously reported efficient transmission of the pathogenic R5 simian-human immunodeficiency virus SHIV(SF162P3N) isolate in Indian rhesus macaques by intravenous and intrarectal inoculations, with a switch to CXCR4 coreceptor usage in ∼50% of infected animals that progressed rapidly to disease....

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Autores principales: Shakirzyanova, Madina, Tsai, Lily, Ren, Wuze, Gettie, Agegneu, Blanchard, James, Cheng-Mayer, Cecilia
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416103/
https://ncbi.nlm.nih.gov/pubmed/22740397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00852-12
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