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Efficient mucosal transmissibility but limited pathogenicity of R5 SHIV(SF162P3N) in Chinese origin rhesus macaques

BACKGROUND: Infection of rhesus macaques (RMs) of Indian origin with SIV or SHIV provided powerful tools to study HIV-1 transmission and disease, and for testing the efficacy of novel drugs, vaccines and prevention strategies. In developing alternative nonhuman primate AIDS models for the CCR5 (R5)-...

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Bibliographic Details
Main Authors: Mumbauer, Alexandra, Gettie, Agegenhu, Blanchard, James, Cheng-Mayer, Cecilia
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622143/
https://ncbi.nlm.nih.gov/pubmed/23221980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31827f1c11
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