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Increased Mucosal Transmission but Not Enhanced Pathogenicity of the CCR5-Tropic, Simian AIDS-Inducing Simian/Human Immunodeficiency Virus SHIV(SF162P3) Maps to Envelope gp120

Through rapid serial transfer in vivo, the chimeric CCR5-tropic simian/human immunodeficiency virus SHIV(SF162) evolved from a virus that is nonpathogenic and poorly transmissible across the vaginal mucosa to a variant that still maintains CCR5 usage but which is now pathogenic and establishes intra...

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Udgivet i:J Virol
Principais autores: Hsu, Mayla, Harouse, Janet M., Gettie, Agegnehu, Buckner, Clarisa, Blanchard, James, Cheng-Mayer, Cecilia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140803/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12502815/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.2.989-998.2003
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